What are the factors that influence clinical trial participation?

To learn more about the elements of clinical trials research that are of interest to patients, a survey was conducted in the fall of 2023. This survey aimed to provide insight into what types of studies prospective participants would be interested in. The findings from this survey would aim to inform future communications and strategies pertaining to patient recruitment for investigators conducting clinical trials on Lyme and other Tick-borne diseases.

Over a four-week period of collection, 210 participants age 18 and older completed this IRB-approved anonymous survey.

The questions asked questions addressing the following areas: a) factors and obstacles that might influence a decision to participate; b) the type of study they would be interested in (e.g., placebo-controlled trials, a study that guarantees treatment); c) experience of participation in previous clinical trials; d) willingness to participate in future trials for Lyme and other tick-borne diseases. Participants also had the opportunity to share any questions they may have about future clinical trials for Lyme and tick-borne diseases.

The findings from this survey demonstrated a willingness to participate, a desire for studies that address all tick-borne conditions, and the importance of ease of participation.

This survey was developed by Meghan Bradshaw, graduate student researcher at UNC Gillings School of Global Public Health (UNC IRB 23-1991) as an Applied Practicum Experience project with Columbia Lyme CTNCC. Future publication and full report to come.